宫内授精(IUI)是一种治疗不孕症的方法，其中精子在放入子宫之前进行清洗，加工和浓缩。IUI是针对宫颈因素不孕症的女性的一线治疗。宫颈粘液可能太厚或太薄，或者可能不会以足够的量存在。有时，女性的免疫系统会误认为精子会侵入细菌。当发生这种情况时，她的身体会发出自然防御机制来摧毁精子，就好像它是细菌或病毒一样。
IUI时间
IUI计划在排卵期间进行。一旦女性的卵泡成熟，就会注射hCG来刺激排卵，这种情况发生在注射后约36小时。
IUI为男性因素不孕症
IUI通常是轻度男性不育症的首选治疗选择之一 。通常，精子可以集中到足以使受精成为可能。
IUI与生育药物
卵泡刺激素(FSH) 药物如Gonal-F，Follistim或Repronex可用于IUI循环以促进许多卵的发育。FSH的使用取决于夫妻不育的原因，治疗史和许多其他因素。通过血液测试监测经历生育药物刺激(也称为排卵诱导)的患者以测量激素水平和经阴道超声波，其允许医生可视化卵巢和卵泡。由于产蛋量增加，使用FSH的IUI成功率通常高于非药物周期。
IUI和倍数
使用FSH的IUI可以导致高阶多胞胎(三胞胎或更多)，这是我们经常在媒体中听到的。然而，这些倍数通常是由未在生殖内分泌学和不育方面接受过广泛培训的医生进行的循环的结果。
不孕症专家会 仔细监控所有IUI周期，并接受培训，以适当调整药物剂量，以尽量减少多胎的风险。如果多胎分娩的风险太大，有时IUI周期可能被取消或转换为IVF周期。由于医生控制转移到子宫的胚胎数量，因此IVF导致高阶倍数是不寻常的。
Intrauterine Insemination (IUI)
Intrauterine Insemination (IUI) is a treatment for infertility in which sperm are washed, processed and concentrated prior to placement in the uterus. IUI is a first line treatment for women with cervical factor infertility. The cervical mucus may be too thick or thin or it may not be present in adequate quantities. Sometimes the woman’s immune system mistakes sperm for invading germs. When this happens her body dispatches its natural defense mechanisms to destroy the sperm just as if it were a bacteria or virus.
IUI Timing
IUI is planned around the time of ovulation. Once a woman’s follicles mature, an injection of hCG is given to stimulate ovulation, which occurs approximately 36 hours after the injection.
IUI for Male Factor Infertility
IUI is often one of the first treatment choices in cases of mild male infertility. Often, the sperm can be concentrated enough to make fertilization possible.
IUI with Fertility Drugs
Follicle stimulating hormone (FSH) medications such as Gonal-F, Follistim or Repronex may be used in an IUI cycle to encourage the development of numerous eggs. Use of FSH is dependent upon the cause(s) of the couple’s infertility, their treatment history and many other factors. Patients undergoing fertility drug stimulation, also known as ovulation induction, are monitored through blood tests to measure hormone levels, and transvaginal ultrasounds, which allow the physician to visualize the ovaries and follicles. IUI success rates using FSH are usually higher than in non-medicated cycles due to increased egg production.
IUI and Multiples
IUI using FSH can result in high order multiple births (triplets, or more), which we often hear about in the media. Often, however, these multiples are the result of cycles conducted by physicians who are not extensively trained in reproductive endocrinology and infertility.
Our infertility specialists carefully monitor all IUI cycles and are trained to adjust medication dosages appropriately to minimize the risk of multiple births. Sometimes an IUI cycle may be cancelled or converted to an IVF cycle if the risk of multiple births is too great. It is unusual for high order multiples to result from IVF because the physician controls the number of embryos transferred to the uterus.
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